Difluorocarbene-enabled selective Csp 3 –N bond cleavage in aliphatic tertiary amines to access sulfilimines and sulfoximines

Organic Chemistry Frontiers 2026

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Authors: Liang Wang Chen, Yong-Liang Pan, Sheng En Fang, Huan Yuan, Pengju Feng, Bing Shu
DOI: 10.1039/d5qo01551k
Cited by: 1
References: 77

Abstract

A metal-free and efficient method has been developed for the synthesis of sulfilimines and sulfoximines via difluorocarbene enabled selective C sp 3 –N bond cleavage/SN bond formation between tertiary amines and sulfenamide/sulfinamides.

Fields of Study & Subjects

Synthesis and Catalytic Reactions Fluorine in Organic Chemistry Click Chemistry and Applications

Publication details

Journal / source
Organic Chemistry Frontiers
Publisher
Royal Society of Chemistry (RSC)
Volume
13
Issue
6
Pages
1897–1903
Publication date
1 January 2026
Language
EN