Asymmetric synthesis of 4,5-dihydropyrrole derivatives via DKR: DROC of activated aziridines with enaminones

Organic Chemistry Frontiers 2026

View at publisher
Authors: Amit K. Sharma, Poulami Mandal, Ranjan Mali, Noimur Rahman, Nilay Kumar Pal, Manas K. Ghorai
DOI: 10.1039/d5qo01590a
Cited by: 0
References: 64

Abstract

An efficient and highly enantioselective route to 4,5-dihydropyrrole derivatives via DKR assisted domino ring opening cyclization DROC of racemic aziridines with N , N -dimethyl enaminones employing Cu( i )-( S )-XylBINAP as the catalyst system is reported.

Fields of Study & Subjects

Synthesis and Characterization of Pyrroles Synthesis and Catalytic Reactions Advanced Synthetic Organic Chemistry

Publication details

Journal / source
Organic Chemistry Frontiers
Volume
13
Issue
6
Pages
1783–1791
Publication date
1 January 2026
Language
EN