Lewis acid-catalyzed cascade via intercepted Meyer–Schuster O -allenylation and [3,3]-sigmatropic rearrangement: divergent synthesis of 2-alkenylanilines and indoles

Organic Chemistry Frontiers 2026

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Authors: Wen-Bin Xu, Li-Na Yang, Yangshuang Wang, Yu Zhang, Xiao-Han Qiu, Yu-Ning Gao, Ming Bian, Cun-Feng Song, Hui‐Yu Chen, Zhen-Jiang Liu
DOI: 10.1039/d5qo01615k
Cited by: 0
References: 56

Abstract

A Lewis acid-catalyzed cascade reaction of N -aryl hydroxylamines and propargylic alcohols efficiently synthesizes 2-alkenylanilines and polysubstituted indoles in one pot.

Fields of Study & Subjects

Synthesis of Indole Derivatives Organic Chemistry Synthesis Methods Catalytic Alkyne Reactions

Publication details

Journal / source
Organic Chemistry Frontiers
Volume
13
Issue
6
Pages
1792–1799
Publication date
1 January 2026
Language
EN