Fluoroalkylation of steroid derivatives: synthetic strategies, mechanistic trends, and pharmacological perspectives

Organic Chemistry Frontiers 2026

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Authors: Sebastián Barata‐Vallejo, Damian Emilio E. Yerien, Javier A. Ramírez, Al Postigo
DOI: 10.1039/d5qo01669j
Cited by: 3
References: 81

Abstract

Fluorinated steroid chemistry evolved from a niche field into a central discipline linking organic synthesis, medicinal chemistry, and chemical biology. Advances in mechanisms, reagents, and selectivity will expand tools for drug discovery.

Fields of Study & Subjects

Fluorine in Organic Chemistry Synthesis and Characterization of Pyrroles Chemical Synthesis and Analysis

Publication details

Journal / source
Organic Chemistry Frontiers
Publisher
Royal Society of Chemistry (RSC)
Volume
13
Issue
6
Pages
1938–1963
Publication date
1 January 2026
Language
EN