Palladium-catalyzed four-component cascade cyclization and carbonylation of bicyclobutyl (BCB) amides

Organic Chemistry Frontiers 2026

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Authors: Jimmy Wang, Chunxue Pu, Jianfeng Xu, Yan Cao, Wei Chen, Jun Ying
DOI: 10.1039/d5qo01673h
Cited by: 4
References: 29

Abstract

A novel palladium-catalyzed four-component cascade cyclization and carbonylation of bicyclobutyl (BCB) amides has been developed for the rapid construction of functionalized spiroquinolinone scaffolds.

Fields of Study & Subjects

Catalytic C–H Functionalization Methods Catalytic Cross-Coupling Reactions Synthesis and pharmacology of benzodiazepine derivatives

Publication details

Journal / source
Organic Chemistry Frontiers
Publisher
Royal Society of Chemistry (RSC)
Volume
13
Issue
5
Pages
1625–1629
Publication date
1 January 2026
Language
EN