CHA-initiated [3 + 2 + 1] spiroannulation of enaminone with diazo oxindole leading to a concise and divergent synthesis of oxindole spirohydropyridines
Abstract
Presented herein is a concise and selective construction of diverse spirohydropyridine skeletons along with the simultaneous introduction of an oxindole moiety based on the CHA-initiated cascade reaction of an enaminone with a diazo oxindole.
Fields of Study & Subjects
Synthesis and Characterization of Pyrroles
Catalytic C–H Functionalization Methods
Cyclopropane Reaction Mechanisms
Publication details
- Journal / source
- Organic Chemistry Frontiers
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 13
- Issue
- 7
- Pages
- 2152–2158
- Publication date
- 1 January 2026
- Language
- EN