Recent advances in visible-light-induced defluorinative functionalization of α-trifluoromethyl arylalkenes

Organic Chemistry Frontiers 2026 Open access

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Authors: Yanyan He, Leiyang Lv, Zhenhua Jia, Teck Peng Loh
DOI: 10.1039/d5qo01732g
Cited by: 10
References: 208

Abstract

In this perspective, we summarize recent advances in visible-light-driven defluorinative functionalization of α-trifluoromethyl arylalkenes, highlighting the strategies for gem -difluoroalkene synthesis via photoinduced SET and radical–polar crossover.

Fields of Study & Subjects

Fluorine in Organic Chemistry Radical Photochemical Reactions Click Chemistry and Applications

Publication details

Journal / source
Organic Chemistry Frontiers
Publisher
Royal Society of Chemistry (RSC)
Volume
13
Issue
7
Pages
2178–2200
Publication date
1 January 2026
Language
EN