Flow chemistry-assisted visible light-induced radical addition of β-amino iodides with enones en route to efficient construction of cis -2,6-piperidines

Organic Chemistry Frontiers 2026

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Authors: Yufan Yang, Dongxu Wang, Dongyang Jiang, Kaixuan Pan, Yingchen Wang, Luai Ji, Wanshu Wang, Lu Gao, Fu Peng, Zhenlei Song
DOI: 10.1039/d5qo01747e
Cited by: 0
References: 35

Abstract

A visible-light-induced radical coupling of β-amino iodides with enones provides efficient access to 1,5-amino ketones. Combined with continuous-flow chemistry, this scalable strategy enables concise syntheses of two types of cis -2,6-piperidines.

Fields of Study & Subjects

Radical Photochemical Reactions Innovative Microfluidic and Catalytic Techniques Innovation Organic Chemistry Synthesis Methods

Publication details

Journal / source
Organic Chemistry Frontiers
Volume
13
Issue
7
Pages
2102–2107
Publication date
1 January 2026
Language
EN