Rh( iii )-catalyzed enantioselective C–H arylation: atroposelective synthesis of 2-pyridones from diazo compounds

Organic Chemistry Frontiers 2026

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Authors: Zhanwei Fu, Chen-Yu Dou, Xiong Zhou, Feifei Fang, Mu-Peng Luo, Shu-Rong Ban, Shi Cao, Shou-Guo Wang
DOI: 10.1039/d5qo01764e
Cited by: 1
References: 57

Abstract

Chiral Rh( iii ) catalysis enables enantioselective C6–H arylation of 2-pyridones, delivering axially chiral products in excellent yields and ee (up to 99% yield, 99% ee).

Fields of Study & Subjects

Axial and Atropisomeric Chirality Synthesis Catalytic C–H Functionalization Methods Cyclopropane Reaction Mechanisms

Publication details

Journal / source
Organic Chemistry Frontiers
Publisher
Royal Society of Chemistry (RSC)
Volume
13
Issue
7
Pages
2016–2023
Publication date
1 January 2026
Language
EN