Development of bioactive SF/HAp/ZnO scaffolds incorporating succinic acid with potential bone regeneration capabilities

RSC Advances 2026 Open access

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Authors: Sadia Habib, Aysha Arshad, Hafsah Akhtar, Fahad Hussain Alhamoudi, Gülderen Karakuş, Gültekin Gökce, Aqif Anwar Chaudhry, Hamad Khalid, Ather Farooq Khan
DOI: 10.1039/d5ra04926a
Cited by: 1
References: 62

Abstract

biocompatibility studies using calcein, DAPI, and PI staining (live/dead assay) confirmed that the SA-functionalized scaffold was non-toxic and supported high viability of MC3T3-E1 pre-osteoblasts after 48 hours. The findings indicated that the use of succinic acid delayed the degradation time. This multifunctional composite scaffold showed great potential for use in bone tissue engineering.

Fields of Study & Subjects

Bone Tissue Engineering Materials Graphene and Nanomaterials Applications Calcium Carbonate Crystallization and Inhibition

Publication details

Journal / source
RSC Advances
Publisher
Royal Society of Chemistry (RSC)
Volume
16
Issue
11
Pages
9358–9370
Publication date
1 January 2026
Language
EN