Engineering ofloxacin bioavailability through spray-dried HPMC and xanthan gum-based solid dispersions: enhanced solubility and therapeutic efficacy

RSC Advances 2026 Open access

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Authors: Sadia Pervez Lali, Arooj Fatima, Muhammad Sher, Muhammad A. Hussain, Muhammad Tahir Haseeb, Muhammad Naeem‐ul‐Hassan, Fahad M. Alhoshani, Bandar Khaled Sendy, Ibrahim A. Shaaban, A. Hussien Abbas
DOI: 10.1039/d5ra06222e
Cited by: 2
References: 56

Abstract

Polymeric spray-dried dispersions of ofloxacin enhance solubility and bioavailability for improved therapeutic efficacy.

Fields of Study & Subjects

Advanced Drug Delivery Systems Drug Solubulity and Delivery Systems Inhalation and Respiratory Drug Delivery

Publication details

Journal / source
RSC Advances
Publisher
Royal Society of Chemistry (RSC)
Volume
16
Issue
7
Pages
6048–6060
Publication date
1 January 2026
Language
EN