Influence of intramolecular interactions and transition state energetics on the strain-promoted azide–alkyne cycloaddition of 2-aminobenzenesulfonamide-containing cyclononynes
Abstract
[double bond, length as m-dash]Boc, the intramolecular hydrogen bond is maintained in both the X-ray-characterized minor product and its corresponding transition state, and the calculated product ratios coincided with the experimental data.
Fields of Study & Subjects
Click Chemistry and Applications
Cyclization and Aryne Chemistry
Chemical Reactions and Mechanisms
Publication details
- Journal / source
- RSC Advances
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 16
- Issue
- 2
- Pages
- 1030–1037
- Publication date
- 1 January 2026
- Language
- EN