Novel diazenyl chalcones with a 2-arylidene hydrazineylidene thiazole moiety: synthesis, anticancer potential, spectroscopic characterisation, and molecular docking studies

RSC Advances 2026 Open access

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Authors: Mariem Mohamed El-Samoly, Esmail M. El-Fakharany, Yousra A. El-Maradny, Abdallah E. Abdallah, F. A. Taher, Nadia T. A. Dawoud, Doaa R. Lotfy
DOI: 10.1039/d5ra07769a
Cited by: 1
References: 34

Abstract

. Compounds 4a and 4b demonstrated relatively lower scores; however, compound 5a revealed markedly worse performance in comparison to other derivatives. Finally, these findings should be regarded as preliminary, indicating promising biological potential but not confirming any specific mechanism of action.

Fields of Study & Subjects

Synthesis and biological activity Nonlinear Optical Materials Research Synthesis of Tetrazole Derivatives

Publication details

Journal / source
RSC Advances
Publisher
Royal Society of Chemistry (RSC)
Volume
16
Issue
5
Pages
3894–3908
Publication date
1 January 2026
Language
EN