Rhenium-186-labeled ortho -hydroxythiobenzhydrazide: a potential theranostic agent for use in metastatic breast cancer

RSC Advances 2026 Open access

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Authors: Arpit Mitra, Avik Chakraborty, Trupti S. Upadhye, Sudeep Sahu, Megha Tawate, Sudipta Chakraborty, Rubel Chakravarty, K. V. Vimalnath, Somnath Kar, Dolan Sengupta, Snigdha Gangopadhyay, Sanchita Goswami
+2 more P. K. Gangopadhyay, Sharmila Banerjee
DOI: 10.1039/d5ra07970e
Cited by: 1
References: 50

Abstract

studies involved biodistribution analyses in SCID mice bearing MCF-7 induced human breast cancer xenografts. The pharmacokinetics revealed significant and prolonged tumour uptake, with SPECT/CT imaging showing plasma clearance within 24 hours and minimal retention in the liver and bladder.

Fields of Study & Subjects

Radiopharmaceutical Chemistry and Applications Nanoplatforms for cancer theranostics Metal complexes synthesis and properties

Publication details

Journal / source
RSC Advances
Publisher
Royal Society of Chemistry (RSC)
Volume
16
Issue
22
Pages
20241–20256
Publication date
1 January 2026
Language
EN