Hyaluronan like polysaccharide based nanodrugs with enhanced CD44 avidity for image-guided drug delivery to breast cancer

RSC Advances 2026 Open access

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Authors: Chia-Wei Yang, A. K. M. Atique Ullah, Xuefei Huang
DOI: 10.1039/d5ra07975f
Cited by: 3
References: 62

Abstract

experiments with an orthotopic breast cancer model demonstrated the superior tumor-targeting capability of G2-Sal-ICG and its ability to significantly suppress tumor growth. Our findings suggested G2-Sal-ICG is a promising theranostic nanodrug for CD44-targeted therapy, combining efficient drug delivery with real-time non-invasive imaging, thus highlighting its potential for clinical applications in breast cancer treatment.

Fields of Study & Subjects

Nanoplatforms for cancer theranostics Proteoglycans and glycosaminoglycans research Nanoparticle-Based Drug Delivery

Publication details

Journal / source
RSC Advances
Publisher
Royal Society of Chemistry (RSC)
Volume
16
Issue
3
Pages
2904–2914
Publication date
1 January 2026
Language
EN