Gnetumgams A and B: two new 2-phenylbenzofuran derivatives from the lianas of Gnetum montanum with xanthine oxidase inhibitory activity

RSC Advances 2026 Open access

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Authors: Truong Nhat Van Do, Minh Hiền Nguyễn, Minh Hiền Nguyễn, Hai Xuan Nguyen, Nhan Trung Nguyen, Mai Thanh Thi Nguyen, Mai Thanh Thi Nguyen
DOI: 10.1039/d5ra08293e
Cited by: 1
References: 18

Abstract

interactions within the molybdenum cofactor (MoCo) pocket. Molecular docking and dynamics simulations corroborated the experimental findings and underscored gnetumgam B (2) as a promising scaffold for further optimization toward next-generation XO inhibitors.

Fields of Study & Subjects

Gout Hyperuricemia Uric Acid Natural Compound Pharmacology Studies Sesquiterpenes and Asteraceae Studies

Publication details

Journal / source
RSC Advances
Publisher
Royal Society of Chemistry (RSC)
Volume
16
Issue
2
Pages
1255–1263
Publication date
1 January 2026
Language
EN