New oleanane-type saponins from the leaves of Derris trifoliata

RSC Advances 2026 Open access

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Authors: Bui Thi Mai Anh, Nguyen Thi Mai, Phan Kiem, Bui Thi Nha Trang, Bui Thi Thu Trang, Tran Thuy Nga, Bui Huu Tai
DOI: 10.1039/d5ra08300a
Cited by: 1
References: 22

Abstract

led to the isolation of five new oleanane-type saponins, named derristrifosides A-E (1-5). Their chemical structures were elucidated through comprehensive analyses of HR-ESI-MS and one-dimensional and two-dimensional NMR spectra. These new saponins possess a cantoniensistriol-type sapogenin framework, which is rarely found in vascular plants. Compounds 1-5 exhibited weak inhibitory activity against nitric oxide (NO) production in LPS-stimulated RAW 264.7 cells and weak antiproliferative activity against SK-LU-1 and Hep-G2 human cancer cell lines.

Fields of Study & Subjects

Natural product bioactivities and synthesis Bioactive natural compounds Phytochemistry and Biological Activities

Publication details

Journal / source
RSC Advances
Publisher
Royal Society of Chemistry (RSC)
Volume
16
Issue
12
Pages
10887–10894
Publication date
1 January 2026
Language
EN