Stereoselective 15α-hydroxylation of androsta-1,4-diene-3,17-dione by Gibberella sp. for efficient production of 15α-OH-ADD and 15α-OH-AD

RSC Advances 2026 Open access

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Authors: Ran He, Ming Song, Ruicheng Fu, Yueying Jin, Shi Li, Fuju Wang, Guogang Zhang, Yongbo Song, Weizhuo Xu
DOI: 10.1039/d5ra08374e
Cited by: 1
References: 45

Abstract

sp. as a promising biocatalyst for regio- and stereoselective steroid hydroxylation, providing an efficient microbial strategy for high-value steroidal intermediates in pharmaceutical manufacturing.

Fields of Study & Subjects

Steroid Chemistry and Biochemistry Estrogen and related hormone effects Enzyme Catalysis and Immobilization

Publication details

Journal / source
RSC Advances
Publisher
Royal Society of Chemistry (RSC)
Volume
16
Issue
6
Pages
4766–4775
Publication date
1 January 2026
Language
EN