Biphasic dissolving microneedles with cyclodextrin inclusion complexes for enhanced delivery of poorly soluble drugs

RSC Advances 2026 Open access

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Authors: Runze Wang, Jiaqi Cao, Jing Zou, Rui Zhang, Mengmeng Li, Wanglong Zhang, Mintong Guo
DOI: 10.1039/d5ra08424e
Cited by: 1
References: 64

Abstract

for the commercial gel patch). Multiple-dose studies confirmed flexible modulation of the pharmacokinetic profile by adjusting dosing frequency. In conclusion, the FB/HP-β-CD inclusion biphasic DMN system offers an effective approach for transdermal delivery of poorly soluble drugs.

Fields of Study & Subjects

Advancements in Transdermal Drug Delivery Advanced Drug Delivery Systems Drug Solubulity and Delivery Systems

Publication details

Journal / source
RSC Advances
Publisher
Royal Society of Chemistry (RSC)
Volume
16
Issue
9
Pages
8266–8277
Publication date
1 January 2026
Language
EN