Magnetic dipole imaging of magnetite nanoparticles in brain tissue

RSC Advances 2026 Open access

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Authors: Leon Kaub, Stuart A. Gilder, Roger R. Fu, Barbara A. Maher, Gabriel Maxemin, Aaron T. Kuan, Andreas Büttner, S Milz, Christoph Schmitz
DOI: 10.1039/d5ra08546b
Cited by: 2
References: 46

Abstract

to date. In addition, collecting repeat, but slightly offset magnetic field maps resulted in the unique ability to distinguish sources within a sample from contamination and artifacts. By applying this technique to tissue, we demonstrate the detection of magnetic dipole-generating sources in human and rodent brain samples with the QDM. Detected particles span a size range of 60-135 nm, consistent with the larger end of magnetite particle sizes found by electron microscopy. These are the first direct magnetic observations of magnetite nanoparticles in brain tissue using quantum sensing techniques.

Fields of Study & Subjects

Characterization and Applications of Magnetic Nanoparticles Nanoparticle-Based Drug Delivery Geomagnetism and Paleomagnetism Studies

Publication details

Journal / source
RSC Advances
Publisher
Royal Society of Chemistry (RSC)
Volume
16
Issue
2
Pages
983–994
Publication date
1 January 2026
Language
EN