Novel amide-based macrocyclic Co( ii ) complexes: correlating structural, computational, and biological properties through DFT and docking

RSC Advances 2026 Open access

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Authors: Subhash, Manish Kumar, Vandana, A. Radha Rama Devi, Ashu Chaudhary
DOI: 10.1039/d5ra08873a
Cited by: 2
References: 67

Abstract

] displayed the most promising antimicrobial activity with minimal cytotoxic effects. Molecular docking studies further validated the biological results, indicating favourable interactions of the complexes with relevant biomolecular targets. Overall, these findings highlight the therapeutic potential of amide-containing macrocyclic ligands and their cobalt(ii) complexes as promising candidates for antimicrobial applications, selective cytotoxic behaviour, and effective antioxidant activity.

Fields of Study & Subjects

Metal complexes synthesis and properties Metal-Organic Frameworks: Synthesis and Applications Nonlinear Optical Materials Research

Publication details

Journal / source
RSC Advances
Publisher
Royal Society of Chemistry (RSC)
Volume
16
Issue
4
Pages
3169–3191
Publication date
1 January 2026
Language
EN