Pyrazole/pyrimidine derivatives endowed with azobenzenes as dual EGFR T790M and VEGFR-2 inhibitors: anticancer, docking, synthesis, design and ADMET assessments

RSC Advances 2026 Open access

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Authors: Kurls E. Anwer, Mohamed A. Abdelgawad, Felemban Athary Abdulhaleem M, Nour E. A. Abd El-Sattar, Ahmed El-morsy, Tamer Nasr, Mohammed Elmowafy, Khaled El-Adl, Naglaa M. Ahmed
DOI: 10.1039/d5ra08997b
Cited by: 9
References: 57

Abstract

New pyrazole/pyrimidine derivatives endowed with azobenzenes were synthesized using microwave and traditional methods.

Fields of Study & Subjects

Synthesis and biological activity HER2/EGFR in Cancer Research Fibroblast Growth Factor Research

Publication details

Journal / source
RSC Advances
Publisher
Royal Society of Chemistry (RSC)
Volume
16
Issue
13
Pages
11458–11477
Publication date
1 January 2026
Language
EN