Determination of the structure and dynamics of linear polypeptide gramicidin A at atomic-scale resolution

RSC Advances 2026 Open access

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Authors: Bijay Laxmi Pradhan, Prince Sen, Adarsh Kumar, Anirban Bhunia, Krishna Kishor Dey, Manasi Ghosh
DOI: 10.1039/d5ra09180b
Cited by: 1
References: 51

Abstract

C nuclei in the indole rings of l-tryptophan residues exhibited significantly larger values of the principal components of CSA parameters and longer spin-lattice relaxation times. These types of detailed analysis of the structure and dynamics of peptide antibiotics will augment the field of 'NMR crystallography' and will also serve as a foundation for formulating a new class of antimicrobial peptides.

Fields of Study & Subjects

Antimicrobial Peptides and Activities Microbial Natural Products and Biosynthesis Bacterial Genetics and Biotechnology

Publication details

Journal / source
RSC Advances
Publisher
Royal Society of Chemistry (RSC)
Volume
16
Issue
9
Pages
8072–8104
Publication date
1 January 2026
Language
EN