Chemical-enhanced thyroid cell detection using photonic crystal biosensors with phase-change materials

RSC Advances 2026 Open access

Read full text
Authors: Walaa M. Nouman, Fatma A. Sayed, Arafa H. Aly, S.E.-S. Abd El-Ghany, Samira M. Sallam
DOI: 10.1039/d5ra09237j
Cited by: 9
References: 48

Abstract

and a quality factor of 87.875, enabling clear differentiation between malignant and benign cases. The key novelty is comparing THz spectra of liquid and lyophilized plasma, where lyophilization enhances contrast and malignant-benign separation by reducing water masking effects. The results were compared with previous photonic crystal biosensors, showing that the GST-based design offers superior tunability and diagnostic accuracy due to its unique phase-change properties.

Fields of Study & Subjects

Phase-change materials and chalcogenides Photonic Crystal and Fiber Optics Photonic Crystals and Applications

Publication details

Journal / source
RSC Advances
Publisher
Royal Society of Chemistry (RSC)
Volume
16
Issue
11
Pages
10113–10128
Publication date
1 January 2026
Language
EN