Enzyme-cascade-amplified colorimetric biosensing platform for sub-nanomolar methylmercury in environmental waters

RSC Advances 2026 Open access

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Authors: Wanyan Wu, Yan Guo, Lidan Deng, Wenwu Gong, Shunyu Hu, F. Z. Liu, Chang-ye Hui
DOI: 10.1039/d5ra09313a
Cited by: 3
References: 38

Abstract

> 0.98) with negligible matrix effects, enabling direct colorimetric quantification of culture supernatants. Notably, metabolic burden from pigment synthesis dominated the dose-response profile rather than MeHg cytotoxicity. This biosensor offers a cost-effective alternative for screening MeHg in environmental water, with detection limits that far exceed WHO drinking water guidelines and a potential for high-throughput environmental monitoring.

Fields of Study & Subjects

Advanced Nanomaterials in Catalysis bioluminescence and chemiluminescence research Advanced biosensing and bioanalysis techniques

Publication details

Journal / source
RSC Advances
Publisher
Royal Society of Chemistry (RSC)
Volume
16
Issue
3
Pages
2112–2122
Publication date
1 January 2026
Language
EN