Sonogashira breathes easy: a practical room-temperature homogeneous coupling in continuous flow under air

Reaction Chemistry & Engineering 2026

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Authors: Vladimir L. Bondarev, Ivan A Andreev, Olga A. Sherstneva, Alexey А. Festa, Leonid G. Voskressensky, Rafael Luque
DOI: 10.1039/d5re00494b
Cited by: 0
References: 30

Abstract

The Sonogashira cross-coupling reaction is a cornerstone of modern organic synthesis, yet its implementation under mild, scalable, and operationally simple conditions remains a challenge.

Fields of Study & Subjects

Catalytic Cross-Coupling Reactions Innovative Microfluidic and Catalytic Techniques Innovation Catalytic C–H Functionalization Methods

Publication details

Journal / source
Reaction Chemistry & Engineering
Volume
11
Issue
3
Pages
601–607
Publication date
1 January 2026
Language
EN