Hypervalent chalcogenonium organocatalysis for the direct stereoselective synthesis of deoxyglycosides from hemiacetals

Chemical Science 2026 Open access

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Authors: Jennifer I. Johns, Mukul Mahanti, Thomas Hansen, M. Carmen Galán
DOI: 10.1039/d5sc07018j
Cited by: 1
References: 72

Abstract

2-like transition state with a high degree of oxocarbenium ion character, reminiscent of the mechanism observed for glycosyl-modifying enzymes. The methodology is exemplified on the stereoselective synthesis of a tetrasaccharide in 52% yield.

Fields of Study & Subjects

Carbohydrate Chemistry and Synthesis Chemical Synthesis and Reactions Catalysis for Biomass Conversion

Publication details

Journal / source
Chemical Science
Publisher
Royal Society of Chemistry (RSC)
Volume
17
Issue
10
Pages
4991–4997
Publication date
1 January 2026
Language
EN