Chemo-enzymatic one-pot depolymerization of β-chitin

Chemical Science 2026 Open access

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Authors: Joseph Brehm, Richard J. Lewis, Alan F. Scott, David J. Morgan, Thomas E. Davies, Nigel G. J. Richards, Graham John Hutchings
DOI: 10.1039/d5sc07429k
Cited by: 0
References: 50

Abstract

over Pd-based nanoalloys, is used by a lytic polysaccharide monooxygenase (LPMO) to convert chitin into soluble oligosaccharide fragments. Our approach, which minimizes oxidative damage to the enzyme, eliminates the need for atom-inefficient and energy intensive approaches to chitin depolymerization, potentially achieving substantial environmental and economic savings. The simplicity of this chemo-catalyst/enzyme cascade has significant advantages for accessing chitin as a bio-carbon resource.

Fields of Study & Subjects

Studies on Chitinases and Chitosanases Enzyme Catalysis and Immobilization Biofuel production and bioconversion

Publication details

Journal / source
Chemical Science
Volume
17
Issue
11
Pages
5510–5517
Publication date
1 January 2026
Language
EN