Remote α- and β-C(sp 3 )–H alkenylation of amines via visible-light supported paired electrolysis
Abstract
, a XAT reagent capable of activation of aryl halide to provide aryl radical species. Cathodic reduction of a Ni(i) intermediate to the Ni(0) complex allows closing the Ni-catalyzed cycle, enabling the execution of the cross-coupling stage leading to a C-H functionalized amine derivative. The developed conditions enable precise synchronization of anodic and cathodic catalytic cycles occurring in the presented variant of paired electrolysis, which has been a significant challenge until now.
Fields of Study & Subjects
Radical Photochemical Reactions
Catalytic C–H Functionalization Methods
Sulfur-Based Synthesis Techniques
Publication details
- Journal / source
- Chemical Science
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 17
- Issue
- 12
- Pages
- 6017–6042
- Publication date
- 1 January 2026
- Language
- EN