Widely-used boronic esters as synthetically-versatile directing groups for C–H activation and hydrogen isotope exchange

Chemical Science 2026 Open access

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Authors: J. Conor Townsley, Connor Smith, David M. Lindsay, Gemma M. Liwicki, Nicholas D. Measom, Laura C. Paterson, William J. Kerr
DOI: 10.1039/d5sc09113f
Cited by: 0
References: 52

Abstract

We report the first use of accessible boronic esters as effective directing groups for C–H activation and hydrogen isotope exchange. A chelated NHC/phosphine Ir catalyst system delivers selective ortho -C-sp 2 activation with a range of substrates.

Fields of Study & Subjects

Catalytic C–H Functionalization Methods Organometallic Complex Synthesis and Catalysis Oxidative Organic Chemistry Reactions

Publication details

Journal / source
Chemical Science
Volume
17
Issue
10
Pages
5213–5219
Publication date
1 January 2026
Language
EN