Reductive desymmetric silylation of biaryl bis(triflates) enabled by a chiral nickel/picolinamide complex

Chemical Science 2026 Open access

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Authors: Zhe Chen, Junjie Zhang, Chuan Wang
DOI: 10.1039/d5sc09250g
Cited by: 1
References: 97

Abstract

Reductive desymmetric silylation of biaryl triflates has been realized by employing a chiral nickel/picolinamide as a catalyst, providing highly enantioenriched axially chiral platform molecules for various downstream derivatizations.

Fields of Study & Subjects

Axial and Atropisomeric Chirality Synthesis Catalytic Cross-Coupling Reactions Asymmetric Synthesis and Catalysis

Publication details

Journal / source
Chemical Science
Publisher
Royal Society of Chemistry (RSC)
Volume
17
Issue
13
Pages
6710–6716
Publication date
1 January 2026
Language
EN