L -region-selective annulative π-extension through dearomative activation of polycyclic aromatic hydrocarbons

Chemical Science 2026 Open access

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Authors: Kanami Nakata, Wataru Matsuoka, 伊藤 英人, Kenichiro Itami
DOI: 10.1039/d5sc09309k
Cited by: 3
References: 75

Abstract

Annulative π-extension (APEX) reaction is a useful aromatic ring-fusion method for the synthesis of large polycyclic aromatic hydrocarbons (PAHs) from unfunctionalized small PAHs.

Fields of Study & Subjects

Synthesis of heterocyclic compounds Catalytic C–H Functionalization Methods Synthesis and Properties of Aromatic Compounds

Publication details

Journal / source
Chemical Science
Publisher
Royal Society of Chemistry (RSC)
Volume
17
Issue
8
Pages
3998–4003
Publication date
1 January 2026
Language
EN