Deoxygenative phosphonation of ketones by titanium
Abstract
)-P coupling of ketones with secondary phosphine oxides. The transformation proceeds under mild conditions and shows good compatibility with carbonyl substrates, including cyclic and acyclic ketones, as well as aliphatic aldehydes. Functionalities such as carboxyl, acetal, alkyne, sulfonate, phenol, and alcohol are well tolerated.
Fields of Study & Subjects
Organophosphorus compounds synthesis
Synthesis and characterization of novel inorganic/organometallic compounds
Catalytic Cross-Coupling Reactions
Publication details
- Journal / source
- Chemical Science
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 17
- Issue
- 14
- Pages
- 7236–7243
- Publication date
- 1 January 2026
- Language
- EN