Stereospecific alkenylation of carboranes: copper-catalyzed access to pyridylcarboranyl alkenes
Abstract
-alkenylcarboranes are accessible by this protocol, among which the latter are difficult to access by existing methods. The synthetic utility of this methodology was demonstrated by the late-stage modification of amino acids, sugars, and drug molecules. Furthermore, the synthesized carboranylethylene scaffolds exhibit aggregation-induced emission and bright solid-state luminescence, with quantum yields reaching 67%. Thus, this work unveils a Cu(i)/Cu(iii) catalytic model for the C-H activation of carboranes and establishes pyridylcarborane-alkene hybrids as a new class of functional, bioisosteric architectures.
Fields of Study & Subjects
Boron Compounds in Chemistry
Organoboron and organosilicon chemistry
Catalytic C–H Functionalization Methods
Publication details
- Journal / source
- Chemical Science
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 17
- Issue
- 14
- Pages
- 7194–7202
- Publication date
- 1 January 2026
- Language
- EN