An integrated approach of green chemistry and analytical quality-by-design for simultaneous estimation of drugs in a fixed-dose combination by a stability-indicating RP-HPLC method

RSC Sustainability 2026 Open access

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Authors: Varsha Vishnupant Thorat, Sudhakar Maruti Alave, Vijay Arjun Bagul
DOI: 10.1039/d5su00829h
Cited by: 2
References: 39

Abstract

The RP-HPLC analytical method has been developed and validated for the simultaneous quantification of chlorthalidone (CHL), amlodipine (AML) and telmisartan (TEL) in a combination drug formulation.

Fields of Study & Subjects

Analytical Methods in Pharmaceuticals Analytical Chemistry and Chromatography Pesticide Residue Analysis and Safety

Publication details

Journal / source
RSC Sustainability
Publisher
Royal Society of Chemistry (RSC)
Volume
4
Issue
2
Pages
785–802
Publication date
1 January 2026
Language
EN