A modular silk–collagen scaffold to model dorsoventral spinal cord organization using human pluripotent stem cells
Abstract
. While developed for spinal cord modeling, our fabrication approach is generalizable to other tissues and regions of the CNS, enabling spatial control of multiple tissue compartments. We anticipate that long-term culture with added supportive cell types will foster greater complexity and open avenues for future functional and translational applications.
Fields of Study & Subjects
Silk-based biomaterials and applications
Collagen: Extraction and Characterization
3D Printing in Biomedical Research
Publication details
- Journal / source
- Journal of Materials Chemistry B
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 14
- Issue
- 5
- Pages
- 1562–1573
- Publication date
- 1 January 2026
- Language
- EN