Study on the effect of phosphate-doping in wollastonite scaffolds on their physicochemical properties and critical calvarial defect repair
Abstract
degradation rate of the calcium silicate scaffold, and maintained its structural and morphological stability, thereby providing improved osteoconductive capability. The phosphate content significantly influences bone repair outcomes by modulating the degradation behavior and bioactivity of CSi, and 6% phosphate doping is identified as the optimal content, which may balance the structural stability, biodegradation rate, and potent osteogenic capacity. This study provides quantitative design guidelines for developing calcium-silicon-phosphorus (Ca-Si-P)-based bioceramics.
Fields of Study & Subjects
Bone Tissue Engineering Materials
Magnesium Oxide Properties and Applications
Calcium Carbonate Crystallization and Inhibition
Publication details
- Journal / source
- Journal of Materials Chemistry B
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 14
- Issue
- 7
- Pages
- 2219–2230
- Publication date
- 1 January 2026
- Language
- EN