A theranostic endoperoxide agent with targeted singlet oxygen release and concomitant fluorescence signals

Journal of Materials Chemistry B 2026 Open access

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Authors: Shoucai Yan, Yu Si, Xiao Qian, Rensong Sun, Wanwan Wang, Ziang Liu, Yang Wang, Lei Wang, Engin U. Akkaya
DOI: 10.1039/d5tb02315g
Cited by: 0
References: 53

Abstract

levels in cancer cells, the phenylboronic ester undergoes specific cleavage to generate hydroxyl groups. This structural transformation triggers a blue-to-green fluorescence emission change, providing direct visual confirmation of therapeutic activation within the tumor microenvironment.

Fields of Study & Subjects

Nanoplatforms for cancer theranostics Molecular Sensors and Ion Detection Photodynamic Therapy Research Studies

Publication details

Journal / source
Journal of Materials Chemistry B
Volume
14
Issue
8
Pages
2438–2449
Publication date
1 January 2026
Language
EN