An in situ -forming injectable silk hydrogel with a cocktail of chemotherapeutic drugs simultaneously targeting cancer cells and cancer stem cells

Journal of Materials Chemistry B 2026

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Authors: K. Jeyashree, Abhiram Kumar, Jayakumar Rajendran, Kumar Pranav Narayan, Jyotsnendu Giri
DOI: 10.1039/d5tb02316e
Cited by: 1
References: 47

Abstract

silk injectable hydrogel with sustained dual-drug release effectively eliminates both bulk tumor cells and bCSCs, making this injectable silk hydrogel a promising strategy for reducing breast cancer stem cells, which may reduce the chances of recurrence and enhance therapeutic outcomes.

Fields of Study & Subjects

Silk-based biomaterials and applications Hydrogels: synthesis properties applications Nanoplatforms for cancer theranostics

Publication details

Journal / source
Journal of Materials Chemistry B
Publisher
Royal Society of Chemistry (RSC)
Volume
14
Issue
8
Pages
2612–2629
Publication date
1 January 2026
Language
EN