Injectable oligomer-cross-linked chitosan hydrogels for biomedical applications
Abstract
of up to 28 kPa). Furthermore, oligomer-cross-linking facilitated the production of chitosan-based hydrogels with customizable mechanical properties, controllable swelling behavior, and regulated degradation kinetics. Importantly, cell-laden iCsgel demonstrated excellent cytocompatibility and supported cell proliferation. As a proof-of-concept, some oligomers were partially modified with a fluorescent dye before the cross-linking process, resulting in decorated iCsgel. In summary, the established injectable oligomer-cross-linked chitosan hydrogels represent a promising platform with tunable material properties, making them well-suited for applications in tissue engineering and various biomedical fields, including bioprinting.
Fields of Study & Subjects
Hydrogels: synthesis
properties
applications
Tissue Engineering and Regenerative Medicine
3D Printing in Biomedical Research
Publication details
- Journal / source
- Journal of Materials Chemistry B
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 14
- Issue
- 13
- Pages
- 4080–4097
- Publication date
- 1 January 2026
- Language
- EN