Synthesis of β-aminoacrylated betulin derivatives by a spontaneous amino–yne reaction for antifungal applications
Abstract
-substituents has identified them as promising antifungal agents. These findings illustrate an innovative approach for enhancing the antifungal properties of betulin through β-aminoacrylation, thereby enriching its utility in biomedical applications and promoting the sustainable utilization of bioresources. This study demonstrates that combining an amino-yne reaction with biocompounds facilitates the development of novel biomolecules, indicating their potential for application in the biomedical field and advancing the sustainable development of antimicrobial compounds.
Fields of Study & Subjects
Natural product bioactivities and synthesis
Click Chemistry and Applications
Synthesis and Characterization of Heterocyclic Compounds
Publication details
- Journal / source
- Journal of Materials Chemistry B
- Volume
- 14
- Issue
- 11
- Pages
- 3480–3489
- Publication date
- 1 January 2026
- Language
- EN