Molybdenum nanoclusters as potent antioxidants for the treatment of osteoarthritis

Journal of Materials Chemistry B 2026

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Authors: Hui Yang, Wei Liu, Renwei Wang, Binbin Zhang, Wenge Wang, Jianlin Wu, Peng Jiang, Yandong Zhao, Xu Liang, Xiaotong Feng, Huawei Zhang
DOI: 10.1039/d5tb02482j
Cited by: 1
References: 49

Abstract

destabilization of the medial meniscus (DMM), and MNs treatment effectively prevented and even reversed OA progression by restoring redox balance and promoting M2-dominant macrophage polarization in the synovium. Collectively, these findings demonstrate that MNs serve as safe and multifunctional nano-antioxidants with dual redox-regulatory and immunomodulatory effects, suggesting a promising therapeutic strategy for OA and other inflammation-related diseases associated with oxidative stress.

Fields of Study & Subjects

Polyoxometalates: Synthesis and Applications Metalloenzymes and iron-sulfur proteins Inorganic Chemistry and Materials

Publication details

Journal / source
Journal of Materials Chemistry B
Publisher
Royal Society of Chemistry (RSC)
Volume
14
Issue
10
Pages
3210–3226
Publication date
1 January 2026
Language
EN