Biodegradable polyurethane nerve conduits functionalized with NDP-MSH-loaded self-assembling peptide hydrogels for peripheral nerve regeneration

Journal of Materials Chemistry B 2026

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Authors: Junhong Li, Jinghan Wang, Xirui Long, Jingjing Lin, Mi Su, Chang Ding, Rongxu Lin, Feng Luo, Jiehua Li, Yanhui Liu, Yanchao Wang, Hong Sheng Tan
DOI: 10.1039/d5tb02626a
Cited by: 0
References: 48

Abstract

A biodegradable BWPU nerve conduit with a pH-responsive self-assembling peptide depot releases NDP-MSH to reduce ROS/apoptosis and promote M2 macrophages, enabling sciatic nerve repair comparable to autografts.

Fields of Study & Subjects

Nerve injury and regeneration Tissue Engineering and Regenerative Medicine Supramolecular Self-Assembly in Materials

Publication details

Journal / source
Journal of Materials Chemistry B
Volume
14
Issue
10
Pages
3265–3284
Publication date
1 January 2026
Language
EN