Controlled release of bone morphogenetic protein-2 improves motor function after traumatic brain injury in a rat model

Journal of Materials Chemistry B 2026 Open access

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Authors: Jakob M. Townsend, Jasmine Z. Deng, Scott Barbay, Brian T. Andrews, David J. Guggenmos, Randolph J. Nudo, Michael S. Detamore
DOI: 10.1039/d5tb02643a
Cited by: 2
References: 68

Abstract

< 0.05). Overall, hydrogels with controlled release of BMP-2 may provide neuroprotective benefits in TBI treatment. Future studies will explore BMP-2 delivery strategies to enhance both bone and brain recovery in rat TBI studies.

Fields of Study & Subjects

Traumatic Brain Injury and Neurovascular Disturbances S100 Proteins and Annexins Neurogenesis and neuroplasticity mechanisms

Publication details

Journal / source
Journal of Materials Chemistry B
Publisher
Royal Society of Chemistry (RSC)
Volume
14
Issue
10
Pages
3129–3146
Publication date
1 January 2026
Language
EN