Ionizable mesoporous silica nanoparticle-mediated siAURKB delivery for colorectal cancer therapy

Journal of Materials Chemistry B 2026

View at publisher
Authors: Yuhao Yao, Yuheng Leng, Xilong Li, Pengcheng Chen, Jinglin Zou, Lei Shi, Dapeng Zhang, Yongsheng Li
DOI: 10.1039/d5tb02754c
Cited by: 2
References: 30

Abstract

An ionizable mesoporous silica nanoparticle (MSN) for siRNA delivery was developed by modifying diethylamino groups onto the surface. After loading with Aurora-B siRNA, the formulated nanomedicine realized effective colorectal cancer therapy.

Fields of Study & Subjects

Nanoparticle-Based Drug Delivery Plant-Derived Bioactive Compounds Mesoporous Materials and Catalysis

Publication details

Journal / source
Journal of Materials Chemistry B
Publisher
Royal Society of Chemistry (RSC)
Volume
14
Issue
11
Pages
3573–3583
Publication date
1 January 2026
Language
EN