Construction of soluble sufentanil microneedles and their analgesic effects in a mouse model of cancer pain

Journal of Materials Chemistry B 2026

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Authors: Ayang Zhao, Yueyue Gao, Ao Zhang, Yuting Rong, Guibo Fan, Rui Xin, Sixun Chen, Liangcan He, Sihua Qi
DOI: 10.1039/d5tb02821c
Cited by: 1
References: 44

Abstract

: This study developed a sodium hyaluronate-based soluble sufentanil microneedle patch with strong mechanical properties and rapid dissolution, which demonstrated effective analgesic efficacy in a model of breast cancer bone metastasis pain, demonstrating its potential as a novel delivery strategy for the future management of breakthrough cancer pain.

Fields of Study & Subjects

Advancements in Transdermal Drug Delivery Flavonoids in Medical Research Polydiacetylene-based materials and applications

Publication details

Journal / source
Journal of Materials Chemistry B
Publisher
Royal Society of Chemistry (RSC)
Volume
14
Issue
13
Pages
4098–4112
Publication date
1 January 2026
Language
EN