Development of a sustained anticancer drug delivery system based on hybridization between diatomite and nanostructured lipid carriers

Journal of Materials Chemistry B 2026

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Authors: Sunggu Kang, Daehyeon Yoo, Yoseph Seo, Daeryul Kwon, Yeeun Woo, Hyeok Ki Kwon, Jungbum Kim, Jinyoung Park, Won Suk Lee, Suk Min Yun, Sang Deuk Lee, Taek Lee
DOI: 10.1039/d5tb02924d
Cited by: 2
References: 58

Abstract

cellular assays demonstrated enhanced cytotoxicity of doxorubicin-loaded cNLC (DOX-cNLC) compared with free DOX, and the DBNC further prolonged DOX exposure and therapeutic efficacy. These findings suggest that the DBNC system holds promise as a pH-responsive DDS to improve the bioavailability and therapeutic duration of hydrophobic anticancer drugs.

Fields of Study & Subjects

Nanoparticle-Based Drug Delivery Mesoporous Materials and Catalysis Advancements in Transdermal Drug Delivery

Publication details

Journal / source
Journal of Materials Chemistry B
Publisher
Royal Society of Chemistry (RSC)
Volume
14
Issue
11
Pages
3442–3453
Publication date
1 January 2026
Language
EN