Bioengineered Escherichia coli Nissle 1917 with hematoporphyrin monomethyl ether for targeted sonodynamic therapy and immune activation in ovarian cancer
Abstract
T cell and elevated IFN-γ levels. Histopathological analysis confirmed the biocompatibility of HW@EcN with minimal off-target toxicity. This bioengineered probiotic platform HW@EcN presents a clinically translatable approach for improving SDT efficacy and immune activation, paving the way for innovative cancer therapies.
Fields of Study & Subjects
Cancer Research and Treatments
Ultrasound and Hyperthermia Applications
Ultrasound and Cavitation Phenomena
Publication details
- Journal / source
- Journal of Materials Chemistry B
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 14
- Issue
- 9
- Pages
- 2977–2987
- Publication date
- 1 January 2026
- Language
- EN