A scoping literature review of toxicological studies on per- and polyfluoroalkyl substances (PFAS)

Environmental Science Advances 2026 Open access

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Authors: Marianthi Papathanasiou, Haralampos Tzoupis, Konstantinos D. Papavasileiou, Francesco Dondero, Dario Greco, Iseult Lynch, Antreas Afantitis, Georgia Melagraki
DOI: 10.1039/d5va00328h
Cited by: 3
References: 205

Abstract

A scoping review of 358 studies shows PFAS persist across humans and model systems, with immunotoxicity and hepatotoxicity as key effects and several alternatives showing toxicity profiles similar to legacy PFAS.

Fields of Study & Subjects

Per- and polyfluoroalkyl substances research Fluorine in Organic Chemistry Effects and risks of endocrine disrupting chemicals

Publication details

Journal / source
Environmental Science Advances
Publisher
Royal Society of Chemistry (RSC)
Volume
5
Issue
6
Pages
1527–1555
Publication date
1 January 2026
Language
EN