A reusable fluorescent biosensor based on a morphology-controlled ZIF-8⊃FAM-DNA film
Abstract
with a detection limit of 3.66 nM (based on the 3σ method). More importantly, the film biosensor can maintain a quenching efficiency of 75.0% and a recovery efficiency of 336.1% after three consecutive quenching-recovery cycles, demonstrating its good repeatability. Furthermore, after being stored in a vacuum for 5 days, the film biosensor retains a recovery efficiency of 415.0%, demonstrating a quite good stability. This work provides a practical and reusable MOF-based sensing platform for biological detection.
Fields of Study & Subjects
Metal-Organic Frameworks: Synthesis and Applications
Advanced biosensing and bioanalysis techniques
Molecular Sensors and Ion Detection
Publication details
- Journal / source
- The Analyst
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 151
- Issue
- 5
- Pages
- 1457–1466
- Publication date
- 1 January 2026
- Language
- EN